反应详情

To a solution of 2-mercaptoethanol (1.5 mL, 1.7 g, 22 mmol) in methanol (30 mL) was added with stirring sodium carbonate (4 g, 38 mmol), followed by 2-(diethylamino)ethyl bromide hydrobromide (5.0 g, 19 mmol). The reaction mixture was stirred overnight at room temperature and then filtered. The filtrate was concentrated under reduced pressure to give 2-[2-(diethylamino)ethylthio]-ethanol as a clear oil.

1. filtrationfiltered
2. concentrationThe filtrate was concentrated under reduced pressure