化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]acetate → {5-[3,3-Bis-(4-methyl-cyclohexyl)-ureido]-[1,3,4]thiadiazol-2-ylsulfanyl}-acetic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl 2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]acetate | HCID 351912 | — |
| 反応物 | 4-methyl-N-(4-methylcyclohexyl)cyclohexan-1-amine | HCID 417228 | — |
| 反応物 | {5-[3,3-Bis-(4-methyl-cyclohexyl)-ureido]-[1,3,4]thiadiazol-2-ylsulfanyl}-acetic acid ethyl ester | HCID 66871997 | — |
| 生成物 | {5-[3,3-Bis-(4-methyl-cyclohexyl)-ureido]-[1,3,4]thiadiazol-2-ylsulfanyl}-acetic acid | HCID 57883670 | — |
反応手順
{5-[3,3-Bis-(4-methyl-cyclohexyl)-ureido]-[1,3,4]thiadiazol-2-ylsulfanyl}-acetic acid ethyl ester prepared from bis-(4-methyl-cyclohexyl)-amine and ethyl-2-[5-amino-1,3,4-thiadiazol-2-yl-thio]acetate as described in general procedures (A) and (B). Hydrolysis using general procedure (F) gave the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07872139B2 |
| 出典データセット | uspto-grants-2011_01 |
| ORD ID | ord-efa8ac3321f64a498840c854fe2b9117 |
| 出典メモ | uspto-grants-2011_01 |