Dicyclohexylamine → HCID 57883703, compound

HRID 253774Notes

Reaction equation

HRID 253774 reaction equation
C([O:3][C:4](=[O:30])[CH2:5][CH2:6][CH2:7][S:8][C:9]1[S:10][C:11]([NH:14][C:15]([N:17]([CH:24]2[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]2)[CH:18]2[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]2)=[O:16])=[N:12][N:13]=1)C.C1(NC2CCCCC2)CCCCC1.C(OC(=O)CCCSC1SC(N)=NN=1)C>>[CH:24]1([N:17]([CH:18]2[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]2)[C:15](=[O:16])[NH:14][C:11]2[S:10][C:9]([S:8][CH2:7][CH2:6][CH2:5][C:4]([OH:30])=[O:3])=[N:13][N:12]=2)[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]1

Participants

4

Reactant 3

HCID 7582DicyclohexylamineHCID 42805380HCID 42805380, compoundHCID 66872844HCID 66872844, compound

Product 1

HCID 57883703HCID 57883703, compound

Procedure

4-[5-(3,3-Dicyclohexyl-ureido)-[1,3,4]thiadiazol-2-ylsulfanyl]-butyric acid ethyl ester was pre-pared as described in general procedure (A) using dicyclohexylamine and 4-(5-amino-[1,3,4]thiadiazol-2-ylsulfanyl)-butyric acid ethyl ester. Hydrolysis using general procedure (F) gave the title compound.

Workup

  1. customHydrolysis

Sources & evidence

ORD record
ord-f7e527dd1c424ac3b3dc95aca5ad66df
Source dataset
uspto-grants-2011_01
Patent number
US07872139B2

Reaction notes

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