Methyl 3-mercaptopropionate → HCID 57883606, compound

HRID 253783Notes

Reaction equation

HRID 253783 reaction equation
Br[C:2]1[S:6][C:5]([NH:7][C:8](=[O:22])[N:9]([CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)[CH:10]2[CH2:15][CH2:14][S:13][CH2:12][CH2:11]2)=[N:4][CH:3]=1.[CH3:23][O:24][C:25](=[O:29])[CH2:26][CH2:27][SH:28]>>[CH3:23][O:24][C:25](=[O:29])[CH2:26][CH2:27][S:28][C:2]1[S:6][C:5]([NH:7][C:8]([N:9]([CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]2)[CH:10]2[CH2:15][CH2:14][S:13][CH2:12][CH2:11]2)=[O:22])=[N:4][CH:3]=1

Participants

3

Reactant 2

HCID 18050Methyl 3-mercaptopropionateHCID 57883799HCID 57883799, compound

Product 1

HCID 57883606HCID 57883606, compound

Procedure

Prepared as described in general procedure (D) using 3-(5-bromo-thiazol-2-yl)-1-cyclohexyl-1-(tetrahydro-thiopyran-4-yl)-urea (Example 190) and 3-mercaptopropionic acid methyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-4ab49747d0584b4eb5828ae11f280540
Source dataset
uspto-grants-2011_01
Patent number
US07872139B2

Reaction notes

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