HCID 57883890, compound → HCID 57883968, compound

HRID 253790Notes

Reaction equation

HRID 253790 reaction equation
Br[C:2]1[S:6][C:5]([NH:7][C:8](=[O:23])[N:9]([CH:16]2[CH2:21][CH2:20][CH:19]([CH3:22])[CH2:18][CH2:17]2)[CH:10]2[CH2:15][CH2:14][O:13][CH2:12][CH2:11]2)=[N:4][CH:3]=1.[CH2:24]([O:26][C:27]([C:29]1[N:30]([CH3:35])[C:31]([SH:34])=[N:32][CH:33]=1)=[O:28])[CH3:25]>>[CH2:24]([O:26][C:27]([C:29]1[N:30]([CH3:35])[C:31]([S:34][C:2]2[S:6][C:5]([NH:7][C:8]([N:9]([CH:16]3[CH2:21][CH2:20][CH:19]([CH3:22])[CH2:18][CH2:17]3)[CH:10]3[CH2:15][CH2:14][O:13][CH2:12][CH2:11]3)=[O:23])=[N:4][CH:3]=2)=[N:32][CH:33]=1)=[O:28])[CH3:25]

Participants

3

Reactant 2

HCID 57883890HCID 57883890, compoundHCID 178469865HCID 178469865, compound

Product 1

HCID 57883968HCID 57883968, compound

Procedure

Prepared as described in general procedure (E) using 3-(5-bromo-thiazol-2-yl)-1-(4-methyl-cyclohexyl)-1-(tetrahydro-pyran-4-yl)-urea (Example 203) and 2-mercapto-3-methyl-3H-imidazole-4-carboxylic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-0f1c30b554104abb82c22c647392570f
Source dataset
uspto-grants-2011_01
Patent number
US07872139B2

Reaction notes

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