Methyl 3-mercaptopropionate → HCID 57883620, compound

HRID 253792Notes

Reaction equation

HRID 253792 reaction equation
Br[C:2]1[S:6][C:5]([NH:7][C:8](=[O:26])[N:9]([CH:20]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]2)[CH:10]2[CH2:15][CH2:14][CH:13]([C:16]([F:19])([F:18])[F:17])[CH2:12][CH2:11]2)=[N:4][CH:3]=1.[CH3:27][O:28][C:29](=[O:33])[CH2:30][CH2:31][SH:32]>>[CH3:27][O:28][C:29](=[O:33])[CH2:30][CH2:31][S:32][C:2]1[S:6][C:5]([NH:7][C:8]([N:9]([CH:20]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]2)[CH:10]2[CH2:15][CH2:14][CH:13]([C:16]([F:19])([F:18])[F:17])[CH2:12][CH2:11]2)=[O:26])=[N:4][CH:3]=1

Participants

3

Reactant 2

HCID 18050Methyl 3-mercaptopropionateHCID 57883568HCID 57883568, compound

Product 1

HCID 57883620HCID 57883620, compound

Procedure

Prepared as described in general procedure (D) using 3-(5-bromo-thiazol-2-yl)-1-cyclohexyl-1-(4-trifluoromethyl-cyclohexyl)-urea (Example 204) and 3-mercaptopropionic acid methyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-6ee48669f2d5462f9eb760ecdb43ab04
Source dataset
uspto-grants-2011_01
Patent number
US07872139B2

Reaction notes

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