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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 253795Generated: October 31, 2026

1,1-Dicyclohexyl-3-(4-bromomethyl-thiazol-2-yl)urea → 2-[2-(3,3-Dicyclohexylureido)-thiazol-4-ylmethyl-sulfanyl)-1H-imidazole-4-carboxylic acid ethyl ester

https://huagongshe.com/reaction/253795

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1-Dicyclohexyl-3-(4-bromomethyl-thiazol-2-yl)ureaHCID 86611183—
ReactantHCID 178469909HCID 178469909—
Product2-[2-(3,3-Dicyclohexylureido)-thiazol-4-ylmethyl-sulfanyl)-1H-imidazole-4-carboxylic acid ethyl esterHCID 17846990620%

Reaction Steps

Prepared in 20% yield as described in general procedure (L) from 1,1-dicyclohexyl-3-(4-bromomethyl-thiazol-2-yl)urea and 2-mercapto-1H-imidazole-4-carboxylic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07872139B2
Source datasetuspto-grants-2011_01
ORD IDord-af9b06fa1a2b4028b6dc3251a3fb0a4a
Source noteuspto-grants-2011_01