HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → N-(5-Amino-1H-indazol-3-yl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | N-(5-nitro-1H-indazol-3-yl)benzamide | HCID 22319544 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-(5-Amino-1H-indazol-3-yl)benzamide | HCID 22319522 | 74.6% |
Reaction Steps
N-(5-Amino-1H-indazol-3-yl)benzamide can be obtained as described in Example 4 from 0.6 g of N-(5-nitro-1H-indazol-3-yl)benzamide, 21 ml of ethanol, 4.2 g of ferrous sulfate, 6.6 ml of water and 5.1 ml of 32% aqueous ammonia. 0.4 g of N-(5-amino-1H-indazol-3-yl)benzamide is thus obtained in the form of a yellow powder melting at 116° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06858638B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-8876c742c4ff4aecb28b8f589c22d8b3 |
| Source note | uspto-grants-2005_02 |