HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenesulfonyl chloride → HCID 57883485, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 86761257 | HCID 86761257 | — |
| Product | HCID 57883485 | HCID 57883485 | 84.7% |
Reaction Steps
Prepared as described in general procedure (Q) using 1,1-dicyclohexyl-3-(5-piperazin-1-ylmethyl-thiazol-2-yl)-urea hydrochloride (36 mg, 0.08 mmol), DIEA (42 μL, 0.24 mmol) and benzenesulfonyl chloride (20 μL, 0.16 mmol) to afford 37 mg (68%) of the desired product after purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07872139B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-af8abf9dac1f4ee987ba7cc047ef553e |
| Source note | uspto-grants-2011_01 |