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HRID25387

反应详情

EQUATION

反应方程式

HRID 25387 的结构方程式

REACTANTS

反应物

2
结构：C[Si](C)(C)I
HCID85247

Silane, iodotrimethyl-

C3H9ISi

结构：Cc1nn(C(=O)OC(C)(C)C)c2ccc(NS(=O)(=O)c3ccc(Cl)c(Cl)c3)cc12
HCID22567170

未命名化合物

PRODUCTS

生成物

1
结构：Cc1n[nH]c2ccc(NS(=O)(=O)c3ccc(Cl)c(Cl)c3)cc12
HCID178434307

未命名化合物

收率 80.1%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClC(Cl)Cl
溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

3,4-Dichloro-N-(3-methyl-1H-indazol-5-yl)benzenesulfonamide can be obtained as described in Example 6 from 0.8 g of N-(N-tert-butoxycarbonyl-3-methyl-1H-indazol-5-yl)-3,4-dichlorobenzenesulfonamide, 7.1 ml of chloroform and 0.25 ml of iodotrimethylsilane. 0.5 g of 3,4-dichloro-N-(3-methyl-1H-indazol-5-yl)benzenesulfonamide is thus obtained in the form of a white solid melting at 184° C. (analysis: C14H11Cl2N3O2S.0.04CH2Cl2 % calculated, C, 47.21; H, 3.11; Cl, 19.90; N, 11.80; O, 8.98; S, 9.00. % found C, 47.65; H, 2.56; Cl, 19.97; N, 11.89; S, 8.92).