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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 253875Generated: October 27, 2026

Glycine methyl ester → {[2-(3,3-Dicyclohexyl-ureido)-thiazole-4-carbonyl]-amino}-acetic acid methyl ester

https://huagongshe.com/reaction/253875

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycine methyl esterHCID 69221—
Reactant2-(3,3-Dicyclohexylureido)-thiazole-4-carboxylic acidHCID 57883604—
Product{[2-(3,3-Dicyclohexyl-ureido)-thiazole-4-carbonyl]-amino}-acetic acid methyl esterHCID 5788366330%

Reaction Steps

Prepared in 30% yield (76 mg) as described in general procedure (K) from 2-(3,3-dicyclohexylureido)-thiazole-4-carboxylic acid (210 mg, 0.6 mmol) and glycine methyl ester (HCl salt, 75 mg, 0.6 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07872139B2
Source datasetuspto-grants-2011_01
ORD IDord-3260a57540e746828d97ebf7782f696b
Source noteuspto-grants-2011_01