3-Chloro-N,N-dimethyl-1-propanamine → 1,1-Dicyclohexyl-3-[5-(3-dimethylamino-propylsulfanyl)-thiazol-2-yl]-urea

HRID 253890노트

반응식

HRID 253890 반응식
[CH:1]1([N:7]([CH:19]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)[C:8]([NH:10][C:11]2[S:12][C:13]([S:16]C#N)=[CH:14][N:15]=2)=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.SC[C@@H]([C@@H](CS)O)O.[CH3:33][N:34]([CH3:39])[CH2:35][CH2:36][CH2:37]Cl>>[CH:19]1([N:7]([CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)[C:8]([NH:10][C:11]2[S:12][C:13]([S:16][CH2:37][CH2:36][CH2:35][N:34]([CH3:39])[CH3:33])=[CH:14][N:15]=2)=[O:9])[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1

참가 물질

4

반응물 3

HCID 669603-Chloro-N,N-dimethyl-1-propanamineHCID 439352DithioerythritolHCID 866111921,1-Dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea

생성물 1

HCID 578835221,1-Dicyclohexyl-3-[5-(3-dimethylamino-propylsulfanyl)-thiazol-2-yl]-urea

실험 절차

Prepared as described in general procedure (H) using 1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea, dithioerythritol and 3-dimethylamino-1-propylchloride.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-e1791534d5dc4edab036da76d1587978
출처 데이터셋
uspto-grants-2011_01
특허 번호
US07872139B2

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