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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 253913Generated: October 27, 2026

5-Aminothiazole 2-mercaptopropionic acid ethyl ester → 3-[2-(3-Cyclohexyl-3-cyclopentyl-ureido)-thiazol-5-ylsulfanyl]-propionic acid

https://huagongshe.com/reaction/253913

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Aminothiazole 2-mercaptopropionic acid ethyl esterHCID 86611214—
ReactantHCID 178461294HCID 178461294—
ReactantHCID 178472288HCID 178472288—
Product3-[2-(3-Cyclohexyl-3-cyclopentyl-ureido)-thiazol-5-ylsulfanyl]-propionic acidHCID 57883923—

Reaction Steps

{2-[3-Cyclopentyl-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-propionic acid ethyl ester prepared as described in general procedure (A) using cyclopentyl-(trans-4-methyl-cyclohexyl)-amine and 5-aminothiazole-2-mercaptopropionic acid ethyl ester. Hydrolysis using general procedure (F) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07872139B2
Source datasetuspto-grants-2011_01
ORD IDord-473d0705b0e344ee8751b6beecf8c740
Source noteuspto-grants-2011_01