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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 253939Generated: October 29, 2026

Dimethylsulphamoyl chloride → HCID 178473161, compound

https://huagongshe.com/reaction/253939

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylsulphamoyl chlorideHCID 83372—
ReactantHCID 178473158HCID 178473158—
ProductHCID 178473161HCID 178473161—
ProductHCID 178486169HCID 178486169—

Reaction Steps

{2-[3-(1-Dimethylsulfamoyl-piperidin-4-yl)-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester was prepared in a similar manner to Example 554 using {2-[3-(trans-4-methyl-cyclohexyl)-3-piperidin-4-yl-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester and dimethylsulfamoyl chloride. Hydrolysis using general procedure (F) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07872139B2
Source datasetuspto-grants-2011_01
ORD IDord-531bac1cf8bd41f598dac4df3dfb4e77
Source noteuspto-grants-2011_01