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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 253940Generated: October 31, 2026

Dimethylcarbamoyl Chloride → HCID 178473160, compound

https://huagongshe.com/reaction/253940

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylcarbamoyl ChlorideHCID 6598—
ReactantHCID 178473158HCID 178473158—
ProductHCID 178473160HCID 178473160—
ProductHCID 178484669HCID 178484669—

Reaction Steps

{2-[3-(1-Dimethylcarbamoyl-piperidin-4-yl)-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester was prepared in a similar manner to Example 554 using {2-[3-(trans-4-methyl-cyclohexyl)-3-piperidin-4-yl-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester and dimethylcarbamoyl chloride. Hydrolysis using general procedure (F) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07872139B2
Source datasetuspto-grants-2011_01
ORD IDord-ac110a02c5d84a6fa209e4eee63a0b2a
Source noteuspto-grants-2011_01