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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 253945Generated: October 31, 2026

Dimethylsulphamoyl chloride → HCID 178472293, compound

https://huagongshe.com/reaction/253945

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylsulphamoyl chlorideHCID 83372—
ReactantHCID 178472291HCID 178472291—
ProductHCID 178472293HCID 178472293—
ProductHCID 178486168HCID 178486168—

Reaction Steps

3-{2-[3-(1-Dimethylsulfamoyl-piperidin-4-yl)-3-(trans-4-methyl-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-propionic acid ethyl ester was prepared in a similar manner to Example 554 using 3-{2-[3-(trans-4-methyl-cyclohexyl)-3-piperidin-4-yl-ureido]-thiazol-5-ylsulfanyl}-propionic acid ethyl ester and dimethylsulfamoyl chloride. Hydrolysis using general procedure (F) gave the title compound

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07872139B2
Source datasetuspto-grants-2011_01
ORD IDord-128e21ec342449eb987a046d1e606fa9
Source noteuspto-grants-2011_01