HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-amino-3-benzylamino-1H-indazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | HCID 22567151 | HCID 22567151 | — |
| Solvent | Water | HCID 962 | — |
| Product | 5-amino-3-benzylamino-1H-indazole | HCID 22567300 | 28.1% |
Reaction Steps
5-Amino-3-benzylamino-1H-indazole can be obtained as described in Example 4 from 0.6 g of 3-benzylamino-5-nitro-1H-indazole, 22 ml of ethanol, 4.5 g of ferrous sulfate, 7 ml of water and 5.4 ml of 32% aqueous ammonia. 0.15 g of 5-amino-3-benzylamino-1H-indazole is thus obtained in the form of a brown powder melting at 196° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06858638B2 |
| Source dataset | uspto-grants-2005_02 |
| ORD ID | ord-6e84379ad08745859e7af0c1a96d4bf5 |
| Source note | uspto-grants-2005_02 |