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HRID25407

反应详情

EQUATION

反应方程式

HRID 25407 的结构方程式

REACTANTS

反应物

2
结构：CS(=O)(=O)c1ccccc1S(=O)(=O)Cl
HCID2735178

2-(methylsulfonyl)benzenesulfonyl chloride

C7H7ClO4S2

结构：Nc1ccc2[nH]nc(I)c2c1
HCID178507363

未命名化合物

PRODUCTS

生成物

1
结构：CS(=O)(=O)c1ccccc1S(=O)(=O)Nc1ccc2[nH]nc(I)c2c1
HCID178504719

未命名化合物

收率 82.4%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：c1ccncc1
溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

N-(3-Iodo-1H-indazol-5-yl)-2-methylsulfonylbenzenesulfonamide can be obtained as described in Example 2 from 25.7 g of 5-amino-3-iodo-1H-indazole, 440 ml of pyridine and 25.3 g of 2-(methylsulfonyl)benzenesulfonyl chloride. 39 g of N-(3-iodo-1H-indazol-5-yl)-2-methylsulfonylbenzenesulfonamide are thus obtained in the form of a brown solid (mass analysis: CI: m/z 478 (M+H)+, m/z 495 (M+NH4)+, m/z 260 (base peak)).