Water → HCID 86066890, compound

Participants

Reaction Steps

A solution of 2-bromomethyl-6-(triphenylmethoxymethyl)pyridine (3.04 g, 6.84 mmol) in DMF (25 mL) was treated with sodium azide (650 mg, 10 mmol) and stirred at room temperature for 20 h. The reaction was poured into water (100 mL), extracted with EtOAc (2×50 mL) and the combined organic phase was washed with brine (25 mL), dried (MgSO4) and concentrated in vacuo to give the product (2.75 g, 99%) as a yellow oil; IR νmax (Film)/cm−1 3060, 2103, 1679, 1594, 1448, 1096 and 706; NMR δH (400 MHz, CDCl3) 4.36 (2H, s), 4.39 (2H, s), 7.20-7.33 (10H, m), 7.49-7.52 (6H, m) and 7.72-7.80 (2H, m)

Provenance & Evidence