Hexahydro-1,4-diazepine → HCID 66852590, compound

HRID 254196Notes

Reaction equation

HRID 254196 reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10]([N:13]2[C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[C:15]([CH2:22]Cl)=[CH:14]2)(=[O:12])=[O:11])=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[NH:24]1[CH2:30][CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1>>[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10]([N:13]2[C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[C:15]([CH2:22][N:24]3[CH2:30][CH2:29][CH2:28][NH:27][CH2:26][CH2:25]3)=[CH:14]2)(=[O:12])=[O:11])=[CH:6][CH:5]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 68163Hexahydro-1,4-diazepineHCID 66852350HCID 66852350, compound

Product 1

HCID 66852590HCID 66852590, compound

Procedure

Using essentially the same procedure as described in example 127, 1-(4-isopropylbenzenesulfonyl)-3-chloromethyl-1H-indole was reacted with homopiperazine to obtain the above derivative.

Workup

  1. customto obtain the above derivative

Sources & evidence

ORD record
ord-a6bf2357f05947409a266c4cd6640789
Source dataset
uspto-grants-2011_01
Patent number
US07875605B2

Reaction notes

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