Hexahydro-1,4-diazepine → HCID 66852294, compound

HRID 254197Notes

Reaction equation

HRID 254197 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[S:10]([N:13]1[C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[C:15]([CH2:22]Cl)=[CH:14]1)(=[O:12])=[O:11].[NH:24]1[CH2:30][CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1>>[Br:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[S:10]([N:13]1[C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[C:15]([CH2:22][N:24]2[CH2:30][CH2:29][CH2:28][NH:27][CH2:26][CH2:25]2)=[CH:14]1)(=[O:12])=[O:11]

Participants

3

Reactant 2

HCID 68163Hexahydro-1,4-diazepineHCID 66852352HCID 66852352, compound

Product 1

HCID 66852294HCID 66852294, compound

Procedure

Using essentially the same procedure as described in example 127, 1-(2-Bromo-4-methoxybenzenesulfonyl)-3-chloromethyl-1H-indole was reacted with homopiperazine to obtain the above derivative.

Workup

  1. customto obtain the above derivative

Sources & evidence

ORD record
ord-4f147f5294b44d0f95a4b1cfe1d1de59
Source dataset
uspto-grants-2011_01
Patent number
US07875605B2

Reaction notes

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