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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 254198Generated: October 25, 2026

Hexahydro-1,4-diazepine → 1-[[1-(4-Methylbenzenesulfonyl)-indol-3-yl]methyl][1,4]diazepane

https://huagongshe.com/reaction/254198

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHexahydro-1,4-diazepineHCID 68163—
Reactant3-(chloromethyl)-1-tosyl-1H-indoleHCID 66851995—
Product1-[[1-(4-Methylbenzenesulfonyl)-indol-3-yl]methyl][1,4]diazepaneHCID 66853241—

Reaction Steps

Using essentially the same procedure as described in example 127, 1-(4-methylbenzenesulfonyl)-3-chloromethyl-1H-indole was reacted with homopiperazine to obtain the above derivative.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07875605B2
Source datasetuspto-grants-2011_01
ORD IDord-adecabc3be0b45bc92784c23edc61bfb
Source noteuspto-grants-2011_01