Hexahydro-1,4-diazepine → HCID 66853956, compound

HRID 254199Notes

Reaction equation

HRID 254199 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([S:11]([C:14]1[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=1)(=[O:13])=[O:12])[CH:6]=[C:5]2[CH2:22]Cl.[NH:24]1[CH2:30][CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1>>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([S:11]([C:14]1[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=1)(=[O:13])=[O:12])[CH:6]=[C:5]2[CH2:22][N:24]1[CH2:30][CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 68163Hexahydro-1,4-diazepineHCID 66852547HCID 66852547, compound

Product 1

HCID 66853956HCID 66853956, compound

Procedure

Using essentially the same procedure as described in example 127, 5-Bromo-1-(4-methoxybenzenesulfonyl)-3-chloromethyl-1H-indole was reacted with homopiperazine to obtain the above derivative.

Workup

  1. customto obtain the above derivative

Sources & evidence

ORD record
ord-310e4cc0d3734dc08d41c1b2e7e24347
Source dataset
uspto-grants-2011_01
Patent number
US07875605B2

Reaction notes

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