Hexahydro-1,4-diazepine → HCID 66852878, compound

HRID 254200Notes

Reaction equation

HRID 254200 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([S:11]([C:14]1[CH:19]=[CH:18][C:17]([CH:20]([CH3:22])[CH3:21])=[CH:16][CH:15]=1)(=[O:13])=[O:12])[CH:6]=[C:5]2[CH2:23]Cl.[NH:25]1[CH2:31][CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1>>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([S:11]([C:14]1[CH:19]=[CH:18][C:17]([CH:20]([CH3:22])[CH3:21])=[CH:16][CH:15]=1)(=[O:13])=[O:12])[CH:6]=[C:5]2[CH2:23][N:25]1[CH2:31][CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1

Participants

3

Reactant 2

HCID 68163Hexahydro-1,4-diazepineHCID 66852546HCID 66852546, compound

Product 1

HCID 66852878HCID 66852878, compound

Procedure

Using essentially the same procedure as described in example 127, 5-Bromo-1-(4-isopropylbenzenesulfonyl)-3-chloromethyl-1H-indole was reacted with homopiperazine to obtain the above derivative.

Workup

  1. customto obtain the above derivative

Sources & evidence

ORD record
ord-fe20e1dac86e4c8f9bd7749765ac6156
Source dataset
uspto-grants-2011_01
Patent number
US07875605B2

Reaction notes

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