HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → HCID 66862366, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 4-Chloro-2-fluoro-1-nitrobenzene | HCID 69691 | — |
| Reactant | HCID 178430842 | HCID 178430842 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 66862366 | HCID 66862366 | — |
Reaction Steps
3.75 g 4-Chloro-2-fluoro-nitrobenzene, 3.4 g 2-Cyclohexyl-4-methyl-imidazole, 50 ml acetonitrile and 5 ml triethylamine were heated 6 hours at 60° C. The solvent was distilled off followed by extraction with 100 ml ethylacetate and 2 times 50 ml water. The organic layer was distilled off and the residue chromatographed on silica gel with 5% MeOH/CH2Cl2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07875618B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-8a3b48c174334984b45d44efb9e6f0b1 |
| Source note | uspto-grants-2011_01 |