Formaldehyde → HCID 53318595, compound

Participants

Reaction Steps

Aqueous 37% formalin solution (100 μL) and 0.3 mol Zn[B(CN)H3]2/methanol solution (1.0 mL, 0.3 mmol, prepared from ZnCl2 and NaB(CN)H3) were added to a methanol solution (1 mL) of the compound obtained in Example 15 (7 mg, 0.018 mmol), and stirred at room temperature for 45 minutes. Aqueous 1 N sodium hydroxide solution was added to the reaction liquid, extracted with chloroform, dried with anhydrous magnesium sulfate. The solvent was concentrated under reduced pressure to obtain the entitled compound (2.8 mg, 39%).

Provenance & Evidence