Ethylenediamine → HCID 58951733, compound

HRID 254480Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[C:4]([CH:8]([CH2:11][CH3:12])[C:9]#[N:10])[CH:5]=[CH:6][CH:7]=1.[CH2:13](N)[CH2:14][NH2:15]>>[Br:1][C:2]1[CH:3]=[C:4]([CH:8]([C:9]2[NH:15][CH2:14][CH2:13][N:10]=2)[CH2:11][CH3:12])[CH:5]=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 3301Ethylenediamine

HCID 18680137HCID 18680137, compound

Product 1

HCID 58951733HCID 58951733, compound

Conditions

Temperature: 130 °C

Procedure

rac-2-[1-(3-Bromo-phenyl)-propyl]-4,5-dihydro-1H-imidazole was prepared from 2-(3-bromo-phenyl)-butyronitrile and ethylene diamine in analogy to Example 19 b) but the reaction mixture was heated under microwave irradiation to 130° C. for 1 hour: colourless powder; MS (ISP): 269.0 and 267.0 ((M+H)+.).

Sources & evidence

ORD record: ord-10a006761f0545bfb5e77cf9ae11c4a0
Source dataset: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07875645B2

Reaction notes

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