Ethylenediamine → HCID 58951877, compound

HRID 254488Notes

Reaction equation

HRID 254488 reaction equation
[F:1][C:2]([F:15])([F:14])[C:3]1[CH:4]=[C:5]([CH:9]([CH2:12][CH3:13])[C:10]#[N:11])[CH:6]=[CH:7][CH:8]=1.[CH2:16](N)[CH2:17][NH2:18]>>[F:1][C:2]([F:14])([F:15])[C:3]1[CH:4]=[C:5]([CH:9]([C:10]2[NH:18][CH2:17][CH2:16][N:11]=2)[CH2:12][CH3:13])[CH:6]=[CH:7][CH:8]=1

Participants

3

Procedure

rac-2-[1-(3-Trifluoromethyl-phenyl)-propyl]-4,5-dihydro-1H-imidazole was prepared from rac-2-(3-trifluoromethyl-phenyl)-butyronitrile and ethylene diamine in analogy to Example 22: colourless powder; MS (ISP): 257.0 ((M+H)+.).

Sources & evidence

ORD record
ord-77f84d17e8784a08b080747c29d19dc9
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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