Ethylenediamine → HCID 58951911, compound
Reaction equation
[F:1][C:2]([F:15])([F:14])[C:3]1[CH:8]=[CH:7][C:6]([CH:9]([CH2:12][CH3:13])[C:10]#[N:11])=[CH:5][CH:4]=1.[CH2:16](N)[CH2:17][NH2:18]>>[F:1][C:2]([F:14])([F:15])[C:3]1[CH:4]=[CH:5][C:6]([CH:9]([C:10]2[NH:18][CH2:17][CH2:16][N:11]=2)[CH2:12][CH3:13])=[CH:7][CH:8]=1Participants
3
Procedure
rac-2-[1-(4-Trifluoromethyl-phenyl)-propyl]-4,5-dihydro-1H-imidazole was prepared from rac-2-(4-trifluoromethyl-phenyl)-butyronitrile and ethylene diamine in analogy to Example 22: colourless powder; MS (ISP): 257.0 ((M+H)+.).
Sources & evidence
- ORD record
- ord-1fbe9eafa5384bc99d010be30031835b
- Source dataset
- uspto-grants-2011_01
- Patent number
- US07875645B2
Reaction notes
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