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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 254504Generated: November 1, 2026

Ethylenediamine → 2-(2,6-Difluoro-3-methyl-benzyl)-4,5-dihydro-1H-imidazole

https://huagongshe.com/reaction/254504

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylenediamineHCID 3301—
Reactant2,6-Difluoro-3-MethylphenylacetonitrileHCID 2774158—
Product2-(2,6-Difluoro-3-methyl-benzyl)-4,5-dihydro-1H-imidazoleHCID 58951860—

Reaction Steps

2-(2,6-Difluoro-3-methyl-benzyl)-4,5-dihydro-1H-imidazole was prepared from (2,6-difluoro-3-methyl-phenyl)-acetonitrile and ethylene diamine in analogy to Example 19 b): colourless powder; MS (ISP): 210.1 ((M+H)+.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07875645B2
Source datasetuspto-grants-2011_01
ORD IDord-841ad183ec5344268c400db20bffe5e5
Source noteuspto-grants-2011_01