Ethylenediamine → HCID 58951674, compound

HRID 254506Notes

Reaction equation

HRID 254506 reaction equation
[F:1][C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:12]([CH2:15][CH3:16])[C:13]#[N:14].[CH2:17](N)[CH2:18][NH2:19]>>[F:1][C:2]1[C:7]([C:8]([F:10])([F:11])[F:9])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:12]([C:13]1[NH:19][CH2:18][CH2:17][N:14]=1)[CH2:15][CH3:16]

Participants

3

Reactant 2

HCID 3301EthylenediamineHCID 66855918HCID 66855918, compound

Product 1

HCID 58951674HCID 58951674, compound

Procedure

rac-2-[1-(2-Fluoro-3-trifluoromethyl-phenyl)-propyl]-4,5-dihydro-1H-imidazole was prepared from rac-2-(2-fluoro-3-trifluoromethyl-phenyl)-butyronitrile and ethylene diamine in analogy to Example 19 b): colourless powder; MS (ISP): 275.0 ((M+H)+.).

Sources & evidence

ORD record
ord-e99c81c99c1b47f68ed6d36d8acf9fe4
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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