Ethylenediamine → 2-(2-Chloro-6-methoxy-benzyl)-4,5-dihydro-1H-imidazole

HRID 254513Notes

Reaction equation

HRID 254513 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([O:8][CH3:9])[C:3]=1[CH2:10][C:11]#[N:12].[CH2:13](N)[CH2:14][NH2:15]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([O:8][CH3:9])[C:3]=1[CH2:10][C:11]1[NH:15][CH2:14][CH2:13][N:12]=1

Participants

3

Reactant 2

HCID 3301EthylenediamineHCID 223275112-Chloro-6-methoxybenzeneacetonitrile

Product 1

HCID 247818642-(2-Chloro-6-methoxy-benzyl)-4,5-dihydro-1H-imidazole

Procedure

2-(2-Chloro-6-methoxy-benzyl)-4,5-dihydro-1H-imidazole was prepared from (2-chloro-6-methoxyphenyl)-acetonitrile and ethylene diamine in analogy to Example 19 b): light brown powder; MS (ISP): 224.9 ((M+H)+.).

Sources & evidence

ORD record
ord-8a9ddcff319645be8a59b26eb05c9e1f
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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