Ethylenediamine → 2-(2-Cyclopropyl-benzyl)-4,5-dihydro-1H-imidazole

HRID 254515Notes

Reaction equation

HRID 254515 reaction equation
[CH:1]1([C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[CH2:10][C:11]#[N:12])[CH2:3][CH2:2]1.[CH2:13](N)[CH2:14][NH2:15]>>[CH:1]1([C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[CH2:10][C:11]2[NH:12][CH2:13][CH2:14][N:15]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 3301EthylenediamineHCID 589517752-(2-Cyclopropylphenyl)acetonitrile

Product 1

HCID 247818652-(2-Cyclopropyl-benzyl)-4,5-dihydro-1H-imidazole

Procedure

2-(2-Cyclopropyl-benzyl)-4,5-dihydro-1H-imidazole was prepared from (2-cyclopropyl-phenyl)-acetonitrile and ethylene diamine in analogy to Example 19 b): light brown powder; MS (ISP): 201.4 ((M+H)+.).

Sources & evidence

ORD record
ord-7a1cca8a549e4e7b8557b990f2544e4c
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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