Ethylenediamine → HCID 24781868, compound
Reaction equation
[Cl:1][C:2]1[C:7]([C:8]([F:11])([F:10])[F:9])=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:12][C:13]#[N:14].[CH2:15](N)[CH2:16][NH2:17]>>[Cl:1][C:2]1[C:7]([C:8]([F:10])([F:11])[F:9])=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:12][C:13]1[NH:17][CH2:16][CH2:15][N:14]=1Participants
3
Procedure
2-(2-Chloro-3-trifluoromethyl-benzyl)-4,5-dihydro-1H-imidazole was prepared from (2-chloro-3-trifluoromethylphenyl)-acetonitrile and ethylene diamine in analogy to Example 19 b): white solid; MS (ISP): 262.8 ((M+H)+.).
Sources & evidence
- ORD record
- ord-148b98617f754c9b89fa9dcf0eb1e6a4
- Source dataset
- uspto-grants-2011_01
- Patent number
- US07875645B2
Reaction notes
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