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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 254522Generated: October 30, 2026

Ethylenediamine → Rac-2-[1-(2,3-difluoro-phenyl)-ethyl]-4,5-dihydro-1h-imidazole

https://huagongshe.com/reaction/254522

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylenediamineHCID 3301—
Reactant2-(2,3-Difluorophenyl)propanenitrileHCID 55264232—
ProductRac-2-[1-(2,3-difluoro-phenyl)-ethyl]-4,5-dihydro-1h-imidazoleHCID 58951717—

Reaction Steps

rac-2-[1-(2,3-Difluoro-phenyl)-ethyl]-4,5-dihydro-1H-imidazole was prepared from rac-2-(2,3-difluoro-phenyl)-propionitrile and ethylene diamine in analogy to Example 19 b): off-white solid; MS (EI): 210.1 ((M+H)+.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07875645B2
Source datasetuspto-grants-2011_01
ORD IDord-5066ef2a080b47198c53e593505d8ea6
Source noteuspto-grants-2011_01