Ethylenediamine → 2-(2,6-Dicyclopropyl-benzyl)-4,5-dihydro-1H-imidazole

HRID 254537Notes

Reaction equation

HRID 254537 reaction equation
[CH:1]1([C:4]2[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]3[CH2:12][CH2:11]3)[C:5]=2[CH:13]=[C:14](Br)Br)[CH2:3][CH2:2]1.[CH2:17]([NH2:20])[CH2:18][NH2:19]>>[CH:1]1([C:4]2[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]3[CH2:12][CH2:11]3)[C:5]=2[CH2:13][C:14]2[NH:19][CH2:18][CH2:17][N:20]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 3301EthylenediamineHCID 589517651,3-Dicyclopropyl-2-(2,2-dibromo-vinyl)-benzene

Product 1

HCID 589517102-(2,6-Dicyclopropyl-benzyl)-4,5-dihydro-1H-imidazole

Procedure

2-(2,6-Dicyclopropyl-benzyl)-4,5-dihydro-1H-imidazole was prepared from 1,3-dicyclopropyl-2-(2,2-dibromo-vinyl)-benzene and ethylenediamine in analogy to Example 1e): light yellow crystals; MS (ISP): 241.4 ([M+H]+, 100%).

Sources & evidence

ORD record
ord-eaf78f8da7bd4aea8ac60bb95d585863
Source dataset
uspto-grants-2011_01
Patent number
US07875645B2

Reaction notes

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