Chloroform → N-Ethyl-N-methoxymethylpyrrolidinium hexafluorophosphate

HRID 254899Notes

Reaction equation

HRID 254899 reaction equation
[Cl-].[CH2:2]([N+:4]1([CH2:9][O:10][CH3:11])[CH2:8][CH2:7][CH2:6][CH2:5]1)[CH3:3].[F:12][P-:13]([F:18])([F:17])([F:16])([F:15])[F:14].[Na+].C(Cl)(Cl)Cl>O>[F:12][P-:13]([F:18])([F:17])([F:16])([F:15])[F:14].[CH2:2]([N+:4]1([CH2:9][O:10][CH3:11])[CH2:8][CH2:7][CH2:6][CH2:5]1)[CH3:3]

Participants

5

Reactant 3

HCID 6212ChloroformHCID 5147921Sodium hexafluorophosphateHCID 23116096N-ethyl-N-methoxymethylpyrrolidinium chloride

Product 1

HCID 86618682N-Ethyl-N-methoxymethylpyrrolidinium hexafluorophosphateYield 57.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

In 70.00 g of water was dissolved 35.00 g of N-ethyl-N-methoxymethylpyrrolidinium chloride and thereto was added 32.70 g of sodium hexafluorophosphate to obtain a white solid. The mixture was stirred for 30 minutes, and chloroform was added to the mixture for extraction. The extract was washed with 50 g of water 15 times, thereafter dried, giving 32.60 g of the desired product in the form of a white solid. The product was checked for 1H-NMR as in Example 1.

Workup

  1. customto obtain a white solid
  2. washThe extract was washed with 50 g of water 15 times
  3. customdried

Sources & evidence

ORD record
ord-a1e497204f704234b5c6cb3e877fe378
Source dataset
uspto-grants-2011_01
Patent number
US07875732B2

Reaction notes

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