Triphenylphosphine → HCID 66862942, compound

Participants

Reaction Steps

To a tetrahydrofuran (4 ml) solution of (±)-(1R*,2R*)-1-(3,5-dimethoxy-4-methylphenyl)-1-(methoxymethoxy)-5-phenylpentan-2-ol (142 mg) and methyl2-(4-hydroxyphenoxy)-4-methylbenzoate (249 mg), triphenylphosphine (262 mg) and diethyl azodicarboxylate (0.47 ml) were added, followed by stirring at room temperature overnight. The reaction mixture was concentrated, and the residue was purified with silica gel column chromatography (hexane:ethyl acetate=9:1) to obtain the title compound (128 mg) having the following physical properties.

Provenance & Evidence