6-Aminoquinoline → HCID 178480151, compound

HRID 255018Notes

Reaction equation

[CH3:1][N:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]1[C:8](=[N:13][NH:14][C:15]2[CH:16]=[C:17]3[C:22](=[CH:23][CH:24]=2)N=CC=C3)[C:9]([NH2:12])=[N:10][N:11]=1.NC1C=C2C(=CC=1)N=CC=C2>>[CH3:1][N:2]1[CH:6]=[CH:5][CH:4]=[C:3]1[C:7]1[C:8](=[N:13][NH:14][C:15]2[CH:16]=[CH:17][CH:22]=[CH:23][CH:24]=2)[C:9]([NH2:12])=[N:10][N:11]=1

Participants

Reactant 2

HCID 113736-Aminoquinoline

HCID 178480150HCID 178480150, compound

Product 1

HCID 178480151HCID 178480151, compound

Procedure

In a similar manner, 5-(1-methyl-1H-pyrrol-2-yl)-4-(quinolin-6-ylhydrazono)-4H-pyrazol-3-ylamine was prepared from 6-aminoquinoline (0.25 g, 1.73 mmol) to yield 85 mg of the product. MS (m/z, ES+): 318.3 (M+1, 100%).

Sources & evidence

ORD record: ord-d95b45a0e8a144ffb4afd934bdd3b4cc
Source dataset: uspto-grants-2011_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07875728B2

Reaction notes

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