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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 255063Generated: October 30, 2026

1-Adamantanecarboxylic acid → HCID 178467909, compound

https://huagongshe.com/reaction/255063

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Adamantanecarboxylic acidHCID 13235—
Reactant2-Bromoethyl ethyl etherHCID 61141—
Reactant2-Amino-4,5-dimethyl-1,3-thiazoleHCID 73238—
ProductHCID 178467909HCID 178467909—

Reaction Steps

4,5-Dimethylthiazol-2-ylamine, 1-bromo-2-ethoxyethane and 1-adamantane carboxylic acid were processed as described in Example 47 to afford the title compound. 1H NMR (CDCl3, 500 MHz) δ ppm 1.05 (t, J=7.02 Hz, 3 H) 1.61-1.76 (m, 6 H) 1.84 (d, J=2.50 Hz, 6 H) 1.95-2.03 (m, 3 H) 2.16 (s, 3 H) 2.21 (s, 3 H) 3.43 (q, J=7.07 Hz, 2 H) 3.69 (t, J=5.46 Hz, 2 H) 4.24 (t, J=5.46 Hz, 2 H); MS (ESI) m/z 363 (M=H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07875639B2
Source datasetuspto-grants-2011_01
ORD IDord-fddf9b0644fd4d4689b74f63bb01f978
Source noteuspto-grants-2011_01