HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Adamantanecarboxylic acid → HCID 178467909, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Adamantanecarboxylic acid | HCID 13235 | — |
| Reactant | 2-Bromoethyl ethyl ether | HCID 61141 | — |
| Reactant | 2-Amino-4,5-dimethyl-1,3-thiazole | HCID 73238 | — |
| Product | HCID 178467909 | HCID 178467909 | — |
Reaction Steps
4,5-Dimethylthiazol-2-ylamine, 1-bromo-2-ethoxyethane and 1-adamantane carboxylic acid were processed as described in Example 47 to afford the title compound. 1H NMR (CDCl3, 500 MHz) δ ppm 1.05 (t, J=7.02 Hz, 3 H) 1.61-1.76 (m, 6 H) 1.84 (d, J=2.50 Hz, 6 H) 1.95-2.03 (m, 3 H) 2.16 (s, 3 H) 2.21 (s, 3 H) 3.43 (q, J=7.07 Hz, 2 H) 3.69 (t, J=5.46 Hz, 2 H) 4.24 (t, J=5.46 Hz, 2 H); MS (ESI) m/z 363 (M=H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07875639B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-fddf9b0644fd4d4689b74f63bb01f978 |
| Source note | uspto-grants-2011_01 |