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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 255066Generated: October 31, 2026

2-Amino-4,5-dimethyl-1,3-thiazole → HCID 66860587, compound

https://huagongshe.com/reaction/255066

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-4,5-dimethyl-1,3-thiazoleHCID 73238—
Reactant4-(Bromomethyl)oxaneHCID 2773286—
ProductHCID 66860587HCID 6686058713%

Reaction Conditions

Temperature85 °C

Reaction Steps

A mixture of 4,5-dimethyl-thiazol-2-ylamine (0.36 g, 2.8 mmol) and 4-bromomethyltetrahydropyran (0.75 g, 4.2 mmol) was heated at 85° C. for 16 hours. The residue purified by preparative HPLC to afford 80 mg (13%) of the title compound

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07875639B2
Source datasetuspto-grants-2011_01
ORD IDord-17cbea012b6c479ab97ecc0b9d1203cd
Source noteuspto-grants-2011_01