反应详情

温度

60 °C

To a solution commercially available 5-bromo-6,7-dihydro-5H-benzo[1,2,5]oxadiazol-4-one (1.1 g, 5.1 mmol) in absolute ethanol (60 mL) was added thiourea. The mixture was stirred at 60° C. overnight and then concentrated. The residue was triturated in hexanes and then collected by filtration to afford 1.3 g (90%) of the title compound MS (ESI+) m/z 195 (M+H)+.

1. concentrationconcentrated
2. customThe residue was triturated in hexanes
3. filtrationcollected by filtration