HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 255087Generated: October 30, 2026
2-Amino-4,5-dimethyl-1,3-thiazole → HCID 66858466, compound
https://huagongshe.com/reaction/255087
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Amino-4,5-dimethyl-1,3-thiazole | HCID 73238 | — |
| Reactant | 5-(2-Bromoethoxy)-2,3-dihydro-1,4-benzodioxine | HCID 2735566 | — |
| Product | HCID 66858466 | HCID 66858466 | 13% |
Reaction Steps
A mixture of 5-(2-bromoethoxy)-2,3-dihydro-benzo[1,4]dioxine (1.2 g, 4.7 mmol) and 4,5-dimethyl-thiazol-2-ylamine (0.50 g, 3.9 mmol) was heated at 85° C. for 7 hours. The mixture was cooled to ambient temperature and the residue was recrystallized from ethanol to provide 0.18 g (13%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07875639B2 |
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| Source dataset | uspto-grants-2011_01 |
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| ORD ID | ord-b1cee2fdd61f4312a448299d7d2bc911 |
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| Source note | uspto-grants-2011_01 |
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