HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 255091Generated: October 30, 2026
2-Amino-4,5-dimethyl-1,3-thiazole → 4,5-dimethyl-3-[2-(2,2,2-trifluoro-ethoxy)-ethyl]-3H-thiazol-2-ylideneamine hydrobromide
https://huagongshe.com/reaction/255091
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Amino-4,5-dimethyl-1,3-thiazole | HCID 73238 | — |
| Reactant | 2-(2-Bromoethoxy)-1,1,1-trifluoroethane | HCID 19828971 | — |
| Product | 4,5-dimethyl-3-[2-(2,2,2-trifluoro-ethoxy)-ethyl]-3H-thiazol-2-ylideneamine hydrobromide | HCID 66859271 | — |
Reaction Steps
4,5-Dimethyl-thiazol-2-ylamine and 2-(2-bromo-ethoxy)-1,1,1,-trifluoro-ethane were mixed and heated at 65° C. for 4 hours. The residue was triturated with hexane to afford the title compound. MS (ESI+) m/z 255 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07875639B2 |
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| Source dataset | uspto-grants-2011_01 |
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| ORD ID | ord-5a926797388b4742894c54f2f60bf9cc |
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| Source note | uspto-grants-2011_01 |
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