1-Adamantanecarboxylic acid → HCID 178435113, compound

Participants

Reaction Steps

4,5-Dimethylthiazol-2-ylamine, bromocyclobutane and 1-adamantane carboxylic acid were processed according to the method of Example 47 to afford the title compound. 1H NMR (CDCl3, 500 MHz) δ ppm 0.43-0.53 (m, 3 H) 1.21-1.29 (m, J=7.18, 7.18 Hz, 1 H) 1.60-1.74 (m, J=15.60 Hz, 7 H) 1.82 (d, J=2.81 Hz, 6 H) 1.94-2.03 (m, 3 H) 2.17 (s, 3 H) 2.24 (s, 3 H) 4.06 (d, J=7.18 Hz, 2 H); MS (ESI) m/z 345 (M+H)+.

Provenance & Evidence