1-Adamantanecarboxylic acid → HCID 178448503, compound

Participants

Reaction Steps

4,5-Dimethylthiazol-2-ylamine, 4-bromo-but-1-ene and 1-adamantane carboxylic acid were processed according to the method of Example 47 to afford the title compound. 1H NMR (CDCl3, 500 MHz) δ ppm 1.60-1.76 (m, 6 H) 1.85 (d, J=2.50 Hz, 6 H) 1.94-2.04 (m, 3 H) 2.15 (s, 3 H) 2.20 (s, 3 H) 2.46 (q, J=7.18 Hz, 2 H) 4.16 (t, 2 H) 4.94-5.13 (m, 2 H) 5.75-5.90 (m, 1 H); MS (ESI) m/z 345 (M+H)+.

Provenance & Evidence