1-Adamantanecarboxylic acid → HCID 178435116, compound

Participants

Reaction Steps

4,5-dimethythiazol-2-ylamine, 3-bromomethylpyridine and 1-adamantane carboxylic acid were processed according to the method of Example 47 to afford the title compound. 1H NMR (CDCl3, 500 MHz) δ ppm 1.49-1.71 (m, 6 H) 1.74 (d, J=2.50 Hz, 6 H) 1.85-2.02 (m, 3 H) 2.19 (d, J=11.54 Hz, 6 H) 5.44 (s, 2 H) 7.29 (t, J=7.33 Hz, 2 H) 7.69-7.85 (m, 1 H) 8.49 (d, J=4.68 Hz, 1 H); MS (ESI) m/z 382 (M+H)+

Provenance & Evidence