3-Bromo-1-propanol → HCID 66858520, compound
Reaction equation
[CH3:1][C:2]1[N:3]=[C:4]([NH2:8])[S:5][C:6]=1[CH3:7].[Br:9][CH2:10][CH2:11][CH2:12][OH:13]>>[BrH:9].[NH:8]=[C:4]1[N:3]([CH2:10][CH2:11][CH2:12][OH:13])[C:2]([CH3:1])=[C:6]([CH3:7])[S:5]1Participants
3
Procedure
4,5-dimethyl-thiazol-2-ylamine (2.0 g, 16 mmol) and 3-bromo-propan-1-ol (1.6 mL, 19 mmol) were processed according to the method of Example 46A to afford the title compound.
Sources & evidence
- ORD record
- ord-79a1b8b7669c45bb9da616369f99c9d0
- Source dataset
- uspto-grants-2011_01
- Patent number
- US07875639B2
Reaction notes
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