Methyl iodide → 3-methyl-1,3-benzothiazol-2-imine:hydroiodide

Participants

Reaction Steps

Benzothiazol-2-ylamine (1.0 g, 6.6 mmol) and methyl iodide (0.48 mL, 7.9 mmol) were processed as described in Example 46A to provide 1.2 g (60%) of the title compound. 1H NMR (DMSO-d6, 300 MHz) δ ppm 3.73 (s, 3 H), 7.39-7.47 (m, 1 H), 7.59 dt, J=7.8, 1.0 Hz, 1 H), 7.65-7.71 (m, 1 H), 7.99 (d, J=8.1 Hz, 1 H), 9.99 (s, 2 H); MS (DCI/NH3) m/z 165 (M+H)+.

Provenance & Evidence