HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Lutidine → HCID 17271861, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Lutidine | HCID 7937 | — |
| Reactant | 3-Phenylprop-2-enoyl chloride | HCID 66023 | — |
| Reactant | 3,5-Difluoroaniline | HCID 96595 | — |
| Reactant | (2E)-N-(3-bromophenyl)-3-phenylprop-2-enamide | HCID 874919 | — |
| Product | HCID 17271861 | HCID 17271861 | — |
Reaction Steps
The compound was prepared from 3,5-difluoroaniline (5 g, 38.7 mmol) and cinnamoylchloride (6.45 g, 38.7 mmol) in the presence of 2,6-lutidine (6.8 mL, 58 mmol) as described for Intermediate 18 to give a colorless solid, 8.1 g (81%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07875715B2 |
| Source dataset | uspto-grants-2011_01 |
| ORD ID | ord-131debdfb4f24bfea8f59bf141e425d1 |
| Source note | uspto-grants-2011_01 |